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Once the cells reached 70% confluence, the cells were subcultured and seeded into the apical side of a Transwell plate at a density of 10 4 cells per well

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Allulose stands out because it tastes like sugar, but metabolically behaves very differently, says one of the papers authors, Benjamin Bikman, Ph.D., a metabolic health researcher and professor at Brigham Young University

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Over time, the skin-lightening effect faded: by 6-month follow-up, only 1 out of 16 maintained visible benefit